Ropinirole-d4 (hydrochloride)
Ropinirole-d4 (SKF 101468-d4) hydrochloride is the deuterium labeled Ropinirole hydrochloride. Ropinirole hydrochloride is a potent D3/D2 receptor agonist with a Kiof 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease[1][2].
Product Specifications
CAS Number
1330261-37-4
Product Name Alternative
SKF 101468-d4 (hydrochloride)
UNSPSC
12352005
Target
Dopamine Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(CN(C(CC)([2H])[2H])C(CC)([2H])[2H])C1=C2C(NC(=O)C2)=CC=C1.Cl
Molecular Formula
C16H21D4ClN2O
Molecular Weight
300.86
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
D2 Receptor; D3 Receptor; D4 Receptor
Available Sizes
Frequently Asked Questions
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