S-Adenosyl-L-methionine-13C (dihydrochloride)

S-Adenosyl-L-methionine-13C (S-Adenosyl methionine-13C) dihydrochloride is the 13C labeled S-Adenosyl-L-methionine (HY-B0617) . S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research[1][2][3].

Product Specifications

Product Name Alternative

S-Adenosyl methionine-13C (dihydrochloride) ; Ademetionine-13C (dihydrochloride) ; AdoMet-13C (dihydrochloride)

UNSPSC

12352005

Target

Apoptosis; Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Purity

98.64

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](C[S+]([13CH3])CC[C@H](N)C(O)=O)O3.[Cl-].Cl.Cl

Molecular Formula

C14 13CH25Cl3N6O5S

Molecular Weight

508.81

References & Citations

[1]G M Bressa. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14.|[2]Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6. |[3]Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92 (4) :1515-42.