(-) -Tetrabenazine
(-) -Tetrabenazine ((-) -TBZ; compound 13) is an enantiomer of Tetrabenazine (HY-B0590) . (+) -Tetrabenazine proves 3-fold more active than (-) -Tetrabenazine in inhibiting vesicular monoamine transporter 2 (VMAT2) [1].
Product Specifications
CAS Number
[1026016-84-1]
Product Name Alternative
(-) -TBZ; (3S,11bS) -TBZ; (3S,11bS) -Tetrabenazine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Monoamine Transporter
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.59
Smiles
COC1=C(OC)C=C2CCN(C[C@@H](C(C3)=O)CC(C)C)[C@]3([H])C2=C1
Molecular Formula
C19H27NO3
Molecular Weight
317.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Qian-Sheng Yu, et al. Preparation and Characterization of Tetrabenazine Enantiomers against Vesicular Monoamine Transporter 2. ACS Med Chem Lett. 2010 Mar 31;1 (3) :105-109.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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