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Travoprost-d7

Travoprost-d7 (Fluprostenol isopropyl ester-d7) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].

Product Specifications

Product Name Alternative

Fluprostenol isopropyl ester-d7; AL6221-d7; Flu-Ipr-d7

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Prostaglandin Receptor

Related Pathways

GPCR/G Protein; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Cardiovascular Disease

Smiles

O=C(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@H](COC2=CC=CC(C(F)(F)F)=C2)O)OC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

Molecular Formula

C26H28D7F3O6

Molecular Weight

507.59

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17 (5) :421-32.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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