Tetrahydrozoline (nitrate)
Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].
Product Specifications
CAS Number
118201-38-0
Product Name Alternative
Tetryzoline (nitrate)
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
[O-][N+]([O-])=O.C1(C2CCCC3=C2C=CC=C3)=NCCN1
Molecular Formula
C13H16N3O3-
Molecular Weight
262.28
References & Citations
[1]E Kisilevsky, et al. Anterior and posterior segment vasculopathy associated with long-term use of tetrahydrozoline. CMAJ. 2018 Oct 9;190 (40) :E1208.|[2]Judy Peat, et al.Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS) . Methods Mol Biol. 2010;603:501-8. |[3]Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19 (3) : 2037-2044.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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