Tetrahydrozoline
Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].
Product Specifications
Product Name Alternative
Tetryzoline
UNSPSC
12352005
Hazard Statement
H302
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
99.32
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(C2CCCC3=C2C=CC=C3)=NCCN1
Molecular Formula
C13H16N2
Molecular Weight
200.28
Precautions
H302
References & Citations
[1]E Kisilevsky, et al. Anterior and posterior segment vasculopathy associated with long-term use of tetrahydrozoline. CMAJ. 2018 Oct 9;190 (40) :E1208.|[2]Judy Peat, et al.Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS) . Methods Mol Biol. 2010;603:501-8.|[3]Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19 (3) : 2037-2044.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0556/Tetrahydrozoline-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Launched
CAS Number
[84-22-0]
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