Tetrahydrozoline

Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].

Product Specifications

CAS Number

[84-22-0]

Product Name Alternative

Tetryzoline

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Purity

99.32

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C1(C2CCCC3=C2C=CC=C3)=NCCN1

Molecular Formula

C13H16N2

Molecular Weight

200.28

Precautions

H302

References & Citations

[1]E Kisilevsky, et al. Anterior and posterior segment vasculopathy associated with long-term use of tetrahydrozoline. CMAJ. 2018 Oct 9;190 (40) :E1208.|[2]Judy Peat, et al.Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS) . Methods Mol Biol. 2010;603:501-8.|[3]Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19 (3) : 2037-2044.