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Norethindrone-13C2

Norethindrone-13C2 (Norethisterone-13C2) is 13C labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.

Product Specifications

CAS Number

201741-02-8

Product Name Alternative

Norethisterone-13C2

UNSPSC

12352211

Target

Bacterial; Isotope-Labeled Compounds; Progesterone Receptor

Related Pathways

Anti-infection; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology; Cancer

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](CC[C@@]2(O)[13C]#[13CH])([H])[C@@]3([H])[C@]([C@]4([H])C(CC3)=CC(CC4)=O)([H])CC1

Molecular Formula

C18 13C2H26O2

Molecular Weight

300.40

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Muneyyirci-Delale O, et al. Effect of norethindrone acetate in the treatment of symptomatic endometriosis. Int J Fertil Womens Med. 1998 Jan-Feb;43 (1) :24-7.|[3]Kaser DJ, et al. Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. J Pediatr Adolesc Gynecol. 2012 Apr;25 (2) :105-8.|[4]Maier WE, et al. Pharmacology and toxicology of ethinyl estradiol and norethindrone acetate in experimental animals. Regul Toxicol Pharmacol. 2001 Aug;34 (1) :53-61.|[5]Cheng DC, et al. Norethindrone acetate inhibition of triglyceride synthesis and release by rat hepatocytes. Atherosclerosis. 1983 Jan;46 (1) :41-8.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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