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Octopamine

Octopamine is a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].

Product Specifications

CAS Number

104-14-3

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Adrenergic Receptor; Endogenous Metabolite

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology; Neurological Disease

Purity

99.52

Smiles

OC(C1=CC=C(O)C=C1)CN

Molecular Formula

C8H11NO2

Molecular Weight

153.18

Precautions

H302, H312, H332

References & Citations

[1]Roeder T. Octopamine in invertebrates. Prog Neurobiol. 1999;59 (5) :533-561.|[2]Farooqui T. Octopamine-mediated neuromodulation of insect senses. Neurochem Res. 2007;32 (9) :1511-1529.|[3]Axelrod J, et al. Octopamine. Nature. 1977;265 (5594) :501-504.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Phase 2

Isoform

Human Endogenous Metabolite

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