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Nalidixic acid (sodium salt) (Standard)

Liquiritin (Standard) is the analytical standard of Liquiritin. This product is intended for research and analytical applications. Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2].

Product Specifications

CAS Number

[3374-05-8]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards; Topoisomerase

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection

Smiles

O=C(C1=CN(CC)C2=NC(C)=CC=C2C1=O)O[Na]

Molecular Formula

C12H11N2NaO3

Molecular Weight

254.22

References & Citations

[1]G Y LESHER, et al. 1,8-NAPHTHYRIDINE DERIVATIVES. A NEW CLASS OF CHEMOTHERAPEUTIC AGENTS. J Med Pharm Chem. 1962 Sep;91:1063-5.|[2]Anna Fàbrega, et al. Mechanism of Action of and Resistance to Quinolones. Microb Biotechnol

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Curated Selection

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