(1R,2S,7R) -Sitafloxacin
(R) -Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase[1].
Product Specifications
CAS Number
[127254-10-8]
Product Name Alternative
(1R,2S,7R) -DU-6859a; DU-6857
UNSPSC
12352005
Target
Bacterial; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@@H]4N)CC54CC5)=C3Cl)C1=O)O
Molecular Formula
C19H18ClF2N3O3
Molecular Weight
409.81
References & Citations
[1]T Akasaka, et al. Antibacterial activities and inhibitory effects of sitafloxacin (DU-6859a) and its optical isomers against type II topoisomerases. Antimicrob Agents Chemother. 1998 May;42 (5) :1284-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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