Naftopidil-d7
Naftopidil-d7 (KT-611-d7) is deuterium labeled Naftopidil. Naftopidil (KT-611) is is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil has antiproliferative effects. Naftopidil can be used for the research of prostate hyperplasia[1][2].
Product Specifications
Product Name Alternative
KT-611-d7 ; BM-15275-d7
UNSPSC
12352005
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Smiles
OC(CN1CCN(CC1)C2=C(OC)C=CC=C2)COC3=C([2H])C([2H])=C([2H])C4=C3C([2H])=C([2H])C([2H])=C4[2H]
Molecular Formula
C24H21D7N2O3
Molecular Weight
399.53
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0391S2/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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