Famotidine-13C

Famotidine-13C (MK-208-13C) is 13C labeled Famotidine. Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

Product Specifications

Product Name Alternative

MK-208-13C

UNSPSC

12352005

Target

Histamine Receptor; Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology; Cancer; Cardiovascular Disease

Smiles

O=S(N)(N[13C](CCSCC1=CSC(NC(N)=N)=N1)=N)=O

Molecular Formula

C7 13CH15N7O2S3

Molecular Weight

338.44

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Inan, A., et al., Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo), 2009. 64 (6) : p. 567-70.|[3]Miyata, K., et al., Studies on the mechanism for the gastric mucosal protection by famotidine in rats. Jpn J Pharmacol, 1991. 55 (2) : p. 211-22.