Rebamipide (Standard)

Rebamipide (Standard) is the analytical standard of Rebamipide. This product is intended for research and analytical applications. Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer[1][2].

Product Specifications

CAS Number

[90098-04-7]

UNSPSC

12352100

Target

COX; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Cancer; Inflammation/Immunology

Smiles

OC(C(NC(C1=CC=C(Cl)C=C1)=O)CC(C2=CC=CC=C2N3)=CC3=O)=O

Molecular Formula

C19H15ClN2O4

Molecular Weight

370.79

References & Citations

[1]Sun WH, et al. Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther. 2000 Nov;295 (2) :447-52.|[2]Tanigawa T, et al. Rebamipide inhibits gastric cancer cell growth. Dig Dis Sci. 2007 Jan;52 (1) :240-7.