Sodium butyrate (GMP)
Sodium butyrate (GMP) refers to Sodium butyrate (HY-B0350A) of GMP grade. Small molecules of GMP grade can be used as adjuvants in cell therapy. Sodium Butyrate (sodium butanoate) is an inhibitor of HDAC, possessing anti-tumor activity[1][2][3][4][5].
Product Specifications
Product Name Alternative
Butanoic acid (sodium) (GMP) ; Butyric acid (sodium) (GMP)
UNSPSC
12352211
Target
Apoptosis; Autophagy; Endogenous Metabolite; HDAC
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
CCCC(O[Na])=O
Molecular Formula
C4H7NaO2
Molecular Weight
110.09
References & Citations
[5]Jung HY, et al. Sirtuin-2 inhibition affects hippocampal functions and sodium butyrate ameliorates the reduction in novel object memory, cell proliferation, and neuroblast differentiation. Lab Anim Res. 2016 Dec;32 (4) :224-230|[1]Huang W, et al. Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate. Oncol Lett. 2017 Feb;13 (2) :921-929|[2]Wang P, et al. Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition. Neurobiol Dis. 2017 Dec 14;111:12-25.|[3]Jaworska J, et al. The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. J Neuroinflammation. 2017 Feb 10;14 (1) :34|[4]Qiu Y, et al. Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. In Vitro Cell Dev Biol Anim. 2017 Jan 27
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0350AG/
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
CAS Number
[156-54-7]
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
