Meloxicam-13C6
Meloxicam-13C6 is 13C6-labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively[1][2][3].
Product Specifications
UNSPSC
12352005
Hazard Statement
H301, H360, H412
Target
Apoptosis; Autophagy; COX; Isotope-Labeled Compounds; MMP
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Inflammation/Immunology
Purity
98.93
Smiles
O=C(C1=C(O)[13C]2=[13CH][13CH]=[13CH][13CH]=[13C]2S(N1C)(=O)=O)NC3=NC=C(C)S3
Molecular Formula
C8 13C6H13N3O4S2
Molecular Weight
357.36
Precautions
H301, H360, H412
References & Citations
[1]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40 (6) :980-9. |[2]Iturriaga MP, et al. Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. Oncol Lett. 2017 Aug;14 (2) :2198-2206.|[3]Fikry EM, et al. Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity. J Biochem Mol Toxicol. 2018 Feb;32 (2) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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