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Riluzole hydrochloride (Standard)

Riluzole hydrochloride (Standard) is the analytical standard of Riluzole hydrochloride. This product is intended for research and analytical applications. Riluzole hydrochloride is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

Product Specifications

CAS Number

850608-87-6

UNSPSC

12352100

Target

GABA Receptor; Reference Standards; Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cancer

Smiles

NC1=NC2=CC=C(OC(F)(F)F)C=C2S1.Cl

Molecular Formula

C8H6ClF3N2OS

Molecular Weight

270.66

References & Citations

[1]He Y, et al. Neuroprotective agent riluzole potentiates postsynaptic GABA (A) receptor function. Neuropharmacology. 2002 Feb;42 (2) :199-209.|[2]Thompson JM, et al. Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain. Mol Pain. 2015 Aug 28;11:51.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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