Venlafaxine-d10

Venlafaxine-d10 (Wy 45030-d10) is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT) /norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

Product Specifications

CAS Number

[940297-16-5]

Product Name Alternative

Wy 45030-d10

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Serotonin Transporter

Related Pathways

Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Neurological Disease; Cancer

Smiles

CN(C)CC(C1=CC=C(C=C1)OC)C2(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C2([2H])[2H])O

Molecular Formula

C17H17D10NO2

Molecular Weight

287.46

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121 (1-2) :70-5.|[3]Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25 (6) :871-80.