Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Lidocaine-d6

Lidocaine-d6 (Lignocaine-d6) is deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia[2].

Product Specifications

CAS Number

1215823-29-2

Product Name Alternative

Lignocaine-d6

UNSPSC

12352005

Target

Apoptosis; ERK; Isotope-Labeled Compounds; MEK; NF-κB; Sodium Channel

Related Pathways

Apoptosis; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; NF-κB; Others; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Cardiovascular Disease

Smiles

O=C(NC1=C(C([2H])([2H])[2H])C=CC=C1C([2H])([2H])[2H])CN(CC)CC

Molecular Formula

C14H16D6N2O

Molecular Weight

240.37

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Cummins TR, et al. Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels. J Physiol. 2007 Jul 1;582 (Pt 1) :11.|[3]Sui H, et al. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019 Mar 15;19 (1) :233.|[4]Li Z, et al. Evaluation of the antinociceptive effects of lidocaine and bupivacaine on the tail nerves of healthy rats. Basic Clin Pharmacol Toxicol. 2013 Jul;113 (1) :31-6.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174) Rabbit Polyclonal Antibody (RBITC)
orb1065658 100 µL

Phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174) Rabbit Polyclonal Antibody (RBITC)

Sign In for Pricing
View Details
Zfand2b (NM_026846) Mouse Untagged Clone
MC201128 10 µg

Zfand2b (NM_026846) Mouse Untagged Clone

Sign In for Pricing
View Details
Lentiviral mouse Triml2 shRNA (UAS) - Lentiviral mouse Triml2 shRNA (UAS, RFP) (25)
GTR15284003 1 Vial

Lentiviral mouse Triml2 shRNA (UAS) - Lentiviral mouse Triml2 shRNA (UAS, RFP) (25)

Sign In for Pricing
View Details
RPL36AP43-set siRNA/shRNA/RNAi Lentivector (Human)
41571091 4x 500 ng

RPL36AP43-set siRNA/shRNA/RNAi Lentivector (Human)

Sign In for Pricing
View Details
Lentiviral mouse Ybx2 shRNA (UAS) - Lentiviral mouse Ybx2 shRNA (UAS, RFP) (25)
GTR15141911 1 Vial

Lentiviral mouse Ybx2 shRNA (UAS) - Lentiviral mouse Ybx2 shRNA (UAS, RFP) (25)

Sign In for Pricing
View Details
CYCSP8 AAV siRNA Pooled Vector
17295161 1.0 µg

CYCSP8 AAV siRNA Pooled Vector

Sign In for Pricing
View Details