Azatadine (dimaleate) (Standard)

Azatadine (dimaleate) (Standard) is the analytical standard of Azatadine (dimaleate) . This product is intended for research and analytical applications. Azatadine dimaleate (Azatadine maleate) is an inhibitor of histamine and cholinergic with an IC50 of 6. Azatadine dimaleate has additional antiserotonin activity. Azatadine dimaleate can be studied in research on perennial allergic rhinitis[1][2].

Product Specifications

CAS Number

[3978-86-7]

UNSPSC

12352100

Target

Histamine Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Inflammation/Immunology; Endocrinology

Smiles

O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O.CN1CC/C(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C4\2

Molecular Formula

C28H30N2O8

Molecular Weight

522.55

References & Citations

[1]Wilson JD, et al. Azatadine maleate (Zadine) : evaluation in the management of allergic rhinitis. N Z Med J. 1981 Aug 12;94 (689) :79-81.|[2]Tozzi S, et al. The pharmacology of azatadine, a potential antiallergy drug. Agents Actions. 1974 Oct;4 (4) :264-70.|[3]B. Biehl, et al., Effects of azatadine maleate on subjective appraisal and psychomotor functions relevant to driving performance. Current Medical Research and Opinion, 1979.|[4]JL Hillas, et al., Azatadine maleate in perennial allergic rhinitis: effects on clinical symptoms and choice reaction time. British journal of clinical pharmacology, 1980.