Bestatin (hydrochloride) (Standard)

Bestatin (hydrochloride) (Standard) is the analytical standard of Bestatin (hydrochloride) . This product is intended for research and analytical applications. Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N) /APN and leukotriene A4 hydrolase, used for cancer research.

Product Specifications

CAS Number

[65391-42-6]

Product Name Alternative

Ubenimex hydrochloride (Standard)

UNSPSC

12352005

Target

Aminopeptidase; Antibiotic; Bacterial; Reference Standards

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Infection

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O.Cl

Molecular Formula

C16H25ClN2O4

Molecular Weight

344.83

References & Citations

[1]Hossain A, et al. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 Aug;149:100-6|[2]Qian X, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2016 May-Jun;23 (3) :e680-9.|[3]Lis M, et al. The effects of bestatin on humoral response to sheep erythrocytes in non-treated and cyclophosphamide-immunocompromised mice. Immunopharmacol Immunotoxicol. 2013 Feb;35 (1) :133-8|[4]Poloz Y, et al. Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum. Eukaryot Cell. 2012 Apr;11 (4) :545-57