Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Topiramate-13C

Topiramate-13C (McN 4853-13C) is 13C labeled Topiramate. Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase[1][2][3].

Product Specifications

Product Name Alternative

McN 4853-13C; RWJ 17021-13C

UNSPSC

12352005

Target

Calcium Channel; Carbonic Anhydrase; GABA Receptor; iGluR; Isotope-Labeled Compounds; Potassium Channel; Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

NS(O[13CH2][C@]12[C@](OC(C)(O2)C)([H])[C@@]3([H])[C@@](OC(C)(O3)C)([H])CO1)(=O)=O

Molecular Formula

C11 13CH21NO8S

Molecular Weight

340.35

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Kaminski RM, et al. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 2004 Jun;46 (8) :1097-104.|[3]Lyseng-Williamson KA, et al. Topiramate: a review of its use in the treatment of epilepsy. Drugs. 2007;67 (15) :2231-56.|[4]Nakamura J, et al. Target pharmacology of topiramate, a new antiepileptic drug. Nihon Yakurigaku Zasshi. 2000 Jan;115 (1) :53-7.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

C16orf93 (CCDC189) (NM_001014979) Human Over-expression Lysate
LY423099 100 µg

C16orf93 (CCDC189) (NM_001014979) Human Over-expression Lysate

Sign In for Pricing
View Details
Chromogranin A (CHGA/413), CF594 conjugate, 0.1mg/mL
BNC940413-500 1x 500 µL

Chromogranin A (CHGA/413), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
LGR5 Mouse Monoclonal Antibody [Clone ID: OTI7F2]
CF808752 100 µg

LGR5 Mouse Monoclonal Antibody [Clone ID: OTI7F2]

Sign In for Pricing
View Details
RASSF8 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3F7]
TA505906AM 100 µL

RASSF8 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3F7]

Sign In for Pricing
View Details
PDE6 gamma (PDE6G) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E11]
TA503739AM 100 µL

PDE6 gamma (PDE6G) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E11]

Sign In for Pricing
View Details
SCDGFB (PDGFD) (NM_025208) Human Over-expression Lysate
LC403061 20 µg

SCDGFB (PDGFD) (NM_025208) Human Over-expression Lysate

Sign In for Pricing
View Details