(R) -Doxazosin
(R) -Doxazosin ((R) -UK 33274) is an isomer of Doxazosin, a selective and orally active a1-adrenoceptor agonist. Doxazosin can be used for systemic antihypertensive and ocular hypotensive. Doxazosin exerts its antihypertensive effect by reducing total peripheral resistance by selective postsynaptic a1-blockade, without reducing cardiac output. Doxazosin can significantly lower both standing and supine blood pressure[1].
Product Specifications
CAS Number
70918-17-1
Product Name Alternative
(R) -UK 33274
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)[C@@H]4OC5=CC=CC=C5OC4
Molecular Formula
C23H25N5O5
Molecular Weight
451.48
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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