Hydroxystilbamidine (diisethionate)
Hydroxystilbamidine diisethionate, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine diisethionate is a retrograde fluorescent tracer and histochemical stain[1][2].
Product Specifications
CAS Number
533-22-2
UNSPSC
12352005
Target
DNA Stain; Fluorescent Dye
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
OCCS(=O)(O)=O.N=C(C1=CC=C(/C=C/C2=CC=C(C(N)=N)C=C2)C(O)=C1)N.OCCS(=O)(O)=O
Molecular Formula
C20H28N4O9S2
Molecular Weight
532.59
References & Citations
[1]Folds JD, et al. Immunosuppression by hydroxystilbamidine isethionate, a lysosome-stabilizing, anti-proteolytic, antifungal drug. Infect Immun. 1975 Mar;11 (3) :441-4. |[2]Festy B, et al. Hydroxystilbamidine. A nonintercalating drug as a probe of nucleic acid conformation. Biochemistry. 1973 Nov 20;12 (24) :4827-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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