Hydroxystilbamidine (diisethionate)

Hydroxystilbamidine diisethionate, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine diisethionate is a retrograde fluorescent tracer and histochemical stain[1][2].

Product Specifications

CAS Number

[533-22-2]

UNSPSC

12352005

Target

DNA Stain; Fluorescent Dye

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

OCCS(=O)(O)=O.N=C(C1=CC=C(/C=C/C2=CC=C(C(N)=N)C=C2)C(O)=C1)N.OCCS(=O)(O)=O

Molecular Formula

C20H28N4O9S2

Molecular Weight

532.59

References & Citations

[1]Folds JD, et al. Immunosuppression by hydroxystilbamidine isethionate, a lysosome-stabilizing, anti-proteolytic, antifungal drug. Infect Immun. 1975 Mar;11 (3) :441-4. |[2]Festy B, et al. Hydroxystilbamidine. A nonintercalating drug as a probe of nucleic acid conformation. Biochemistry. 1973 Nov 20;12 (24) :4827-34.