Sodium tetradecyl sulfate (27% in water)

Sodium tetradecyl sulfate (Tergitol 4) is a novel scleroembolic agent and an apoptosis inducer. Sodium tetradecyl sulfate can be used for research on varicose veins and vascular malformation diseases[1][2][3].

Product Specifications

CAS Number

[139-88-8]

Product Name Alternative

Tergitol 4

UNSPSC

12352005

Hazard Statement

H314

Target

Apoptosis

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

O=S(OC(CC(C)C)CCC(CCCC)CC)(O[Na])=O

Molecular Formula

C14H29NaO4S

Molecular Weight

316.43

Precautions

H314

References & Citations

[1]Connor DE, et al. Sirolimus and propranolol inhibit endothelial proliferation while detergent sclerosants induce endothelial activation, microparticle release and apoptosis in vitro. Phlebology. 2020 Sep;35 (8) :566-575.|[2]Zehtabi F, et al. Chitosan-Sodium Tetradecyl Sulfate Hydrogel: Characterization and Preclinical Evaluation of a Novel Sclerosing Embolizing Agent for the Treatment of Endoleaks. Cardiovasc Intervent Radiol. 2017 Apr;40 (4) :576-584. |[3]Morsiani E, et al. Effect of intravenous and intraperivenous injections of sclerosants (sodium tetradecyl sulfate and hydroxy polyethoxy dodecan) on the rat femoral vein. Res Exp Med (Berl) . 1987;187 (6) :439-49. |[4]Zimmet SE. The prevention of cutaneous necrosis following extravasation of hypertonic saline and sodium tetradecyl sulfate. J Dermatol Surg Oncol. 1993 Jul;19 (7) :641-6. |[5]Frullini A, et al. Significant endothelin release in patients treated with foam sclerotherapy. Dermatol Surg. 2012 May;38 (5) :741-7.