Naloxegol-13C, d3
Naloxegol-13C, d3 (NKTR-118-13C, d3) is 13C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation[1][2].
Product Specifications
Product Name Alternative
NKTR-118-13C, d3; AZ-13337019-13C, d3
UNSPSC
12352211
Target
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Smiles
O[C@]12[C@@]34C5=C(C[C@@]2([H])N(CC4)CC=C)C=CC(O)=C5O[C@@]3([H])[C@H](CC1)OCCOCCOCCOCCOCCOCCOCCO[13C]([2H])([2H])[2H]
Molecular Formula
C33 13CH50D3NO11
Molecular Weight
655.80
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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