Gabapentin (hydrochloride) (Standard)

Gabapentin (hydrochloride) (Standard) is the analytical standard of Gabapentin (hydrochloride) . This product is intended for research and analytical applications. Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain[1][2][3].

Product Specifications

CAS Number

[60142-95-2]

UNSPSC

12352100

Target

Calcium Channel; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cancer

Smiles

O=C(O)CC1(CN)CCCCC1.[H]Cl

Molecular Formula

C9H18ClNO2

Molecular Weight

207.70

References & Citations

[1]Fink K, et, al. Inhibition of neuronal Ca (2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun;130 (4) :900-6.|[2]Celikyurt IK, et, al. Gabapentin, A GABA analogue, enhances cognitive performance in mice. Neurosci Lett. 2011 Apr 1;492 (2) :124-8.|[3]Meymandi MS, et, al. Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur J Anaesthesiol. 2008 Feb;25 (2) :129-34.