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Talipexole (dihydrochloride) (Standard)

Talipexole (dihydrochloride) (Standard) is the analytical standard of Talipexole (dihydrochloride) . This product is intended for research and analytical applications. Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.

Product Specifications

CAS Number

36085-73-1

UNSPSC

12352100

Target

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease; Endocrinology

Smiles

NC1=NC2=C(CCN(CC2)CC=C)S1.Cl.Cl

Molecular Formula

C10H17Cl2N3S

Molecular Weight

282.23

References & Citations

[1]Ricci and Taira Adrenoceptor involvement in the cardiovascular responses to B-HT 920 in sinoaortic denervated rats. Gen.Pharmacol. (1999) 32 29.|[2]Eur J Pharmacol. 1997 May 1;325 (2-3) :137-44.|[3]Kohno Y, Fukuzaki K, Kitahara K, Koja T.Anti-tremor activity of talipexole produced by selective dopamine D2 receptor stimulation in cynomolgus monkeys with unilateral lesions in the ventromedial tegmentum.Eur J Pharmacol. 1997 Jan 29;319 (2-3) :197-205.|[4]Momiyama T, Sasa M, Takaori S.Inhibition by talipexole, a thiazolo-azepine derivative, of dopaminergic neurons in the ventral tegmental area.Life Sci. 1991;49 (7) :535-43.|[5]Nishikawa T, Yamada S, Tsuda A, Tanaka M, Koga I, Uchida Y.Chronic treatment with talipexole dihydrochloride on abnormal involuntary movement in humans.Clin Neuropharmacol. 1990 Jun;13 (3) :259-63.|[6]Robertson, G.S., et al., In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release. J Pharmacol Exp Ther, 1993. 264 (3) : p. 1344-51.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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