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O-Deshydroxyethyl bosentan

O-Deshydroxyethyl bosentan is a metabolite of Bosentan , which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors[1].

Product Specifications

CAS Number

174227-14-6

UNSPSC

12352005

Hazard Statement

H361

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=NC(C3=NC=CC=N3)=NC(O)=C2OC4=CC=CC=C4OC)=O

Molecular Formula

C25H25N5O5S

Molecular Weight

507.56

Precautions

P280-P405-P501

References & Citations

[1]Jadhav, S.A, et al. Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist. 2011, 141–149.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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