O-Deshydroxyethyl bosentan
O-Deshydroxyethyl bosentan is a metabolite of Bosentan (HY-A0013), which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors[1].
Product Specifications
CAS Number
[174227-14-6]
UNSPSC
12352005
Hazard Statement
H361
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=NC(C3=NC=CC=N3)=NC(O)=C2OC4=CC=CC=C4OC)=O
Molecular Formula
C25H25N5O5S
Molecular Weight
507.56
Precautions
P280-P405-P501
References & Citations
[1]Jadhav, S.A, et al. Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist. 2011, 141–149.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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