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4-Hydroxyisophthalic acid

4-Hydroxyisophthalic acid activates antioxidant enzymes (such as catalase CAT and superoxide dismutase SOD), scavenges free radicals, and exhibits antioxidant property. 4-Hydroxyisophthalic acid activates AChE and BChE, enhances neuronal function and improves Tau-induced neurobehavioral defects. 4-Hydroxyisophthalic acid improves the cognitive defects, and ameliorates circadian rhythm disorders of fruit flies[1].

Product Specifications

CAS Number

[636-46-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Cholinesterase (ChE) ; SOD

Related Pathways

Immunology/Inflammation; Neuronal Signaling

Field of Research

Neurological Disease

Purity

99.57

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)C1=CC(C(O)=O)=CC=C1O

Molecular Formula

C8H6O5

Molecular Weight

182.13

Precautions

H315, H319, H335

References & Citations

[1]Haddadi M, et al., 4-Hydroxyisophthalic acid from Decalepis hamiltonii rescues the neurobehavioral deficit in transgenic Drosophila model of taupathies. Neurochem Int. 2016 Nov;100:78-90.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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