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Endothelin 1 (swine, human) (TFA)

Product Specifications

UNSPSC Description

Endothelin 1 (swine, human) (TFA) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB[1].

Target Antigen

Endothelin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/endothelin-1-swine-human-tfa.html

Purity

99.95

Solubility

DMSO : 50 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)

Smiles

O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]2([H])NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@](CSSC2)([H])NC([C@@H](NC([C@H](CSSC1)N)=O)CO)=O)=O)CO)=O)CO)=O)CC(C)C)=O)CCSC)=O)CC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)=O)C(C)C)=O)CC3=CC=C(C=C3)O)=O)CC4=CC=CC=C4)=O)N[C@@H](CC5=CN=CN5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F

Molecular Weight

2605.92

References & Citations

[1]Kowalczyk A, et al. The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis. Arch Immunol Ther Exp (Warsz). 2015;63(1):41-52.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P0202A/Endothelin-1-swine-human-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P0202A/Endothelin-1-swine-human-TFA-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

394693-38-0

Available Sizes

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