Endothelin 1 (swine, human) (TFA)
Product Specifications
UNSPSC Description
Endothelin 1 (swine, human) (TFA) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB[1].
Target Antigen
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/endothelin-1-swine-human-tfa.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)
Smiles
O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]2([H])NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@](CSSC2)([H])NC([C@@H](NC([C@H](CSSC1)N)=O)CO)=O)=O)CO)=O)CO)=O)CC(C)C)=O)CCSC)=O)CC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)=O)C(C)C)=O)CC3=CC=C(C=C3)O)=O)CC4=CC=CC=C4)=O)N[C@@H](CC5=CN=CN5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
Molecular Weight
2605.92
References & Citations
[1]Kowalczyk A, et al. The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis. Arch Immunol Ther Exp (Warsz). 2015;63(1):41-52.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P0202A/Endothelin-1-swine-human-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P0202A/Endothelin-1-swine-human-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
394693-38-0
Available Sizes
Curated Selection
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