Nipecotic acid (Standard)
Nipecotic acid (Standard) is the analytical standard of Nipecotic acid. This product is intended for research and analytical applications. Nipecotic acid ((±) -β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro. Nipecotic acid can also directly activate GABAA-like chloride channels, with an EC50 of approximately 300 μM[1][2].
Product Specifications
CAS Number
498-95-3
UNSPSC
12352100
Target
GABA Receptor; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(C1CNCCC1)O
Molecular Formula
C6H11NO2
Molecular Weight
129.16
References & Citations
[1]Barrett-Jolley R, et, al. Nipecotic acid directly activates GABA (A) -like ion channels. Br J Pharmacol. 2001 Jul;133 (5) :673-8.|[2]Dhanawat M, et, al. Design, Synthesis and Enhanced BBB Penetration Studies of L-serine-Tethered Nipecotic Acid-Prodrug. Drug Res (Stuttg) . 2021 Feb;71 (2) :94-103.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940630-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470630-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040965-100 1x 100 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041576-500 1x 500 µL
Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) (KRTH/1576R), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402151-100 1x 100 µL
TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2151), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details