N-Acetyl mesalazine (Standard)

N-Acetyl mesalazine (Standard) (N-Acetyl-5-aminosalicylic acid (Standard) ) is the analytical standard of N-Acetyl mesalazine (HY-66008) . This product is intended for research and analytical applications. N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027) . N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer[1][2].

Product Specifications

CAS Number

[51-59-2]

Product Name Alternative

N-Acetyl-5-aminosalicylic acid (Standard) ; N-Acetyl-ASA (Standard)

UNSPSC

12352005

Target

Drug Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(O)C1=CC(NC(C)=O)=CC=C1O

Molecular Formula

C9H9NO4

Molecular Weight

195.17

References & Citations

[1]Allgayer H, et al. Modulation of base hydroxylation by bile acids and salicylates in a model of human colonic mucosal DNA: putative implications in colonic cancer. Dig Dis Sci. 1999 Apr;44 (4) :761-7.|[2]Fukuda T, et al. Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine. J Gastroenterol Hepatol. 2020 Nov;35 (11) :1878-1885.