SC-560 (Standard)
SC-560 (Standard) is the analytical standard of SC-560. This product is intended for research and analytical applications. SC-560 is a potent and selective COX-1 inhibitor with an IC50 of 9 nM.
Product Specifications
CAS Number
188817-13-2
UNSPSC
12352100
Target
COX; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Cancer
Smiles
FC(C1=NN(C2=CC=C(OC)C=C2)C(C3=CC=C(Cl)C=C3)=C1)(F)F
Molecular Formula
C17H12ClF3N2O
Molecular Weight
352.74
References & Citations
[1]Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95 (22) :13313-8.|[2]Lampiasi N, et al. The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells. Int J Mol Med. 2006 Feb;17 (2) :245-52.|[3]Teng XW, et al. Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat. J Pharm Pharm Sci. 2003 May-Aug;6 (2) :205-10.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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