(Rac) -Roscovitine
(Rac) -Roscovitine ((Rac) -Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac) -Roscovitine binds to the active sites of CDKs competitively with ATP, inhibiting the phosphorylation activity of CDKs. (Rac) -Roscovitine induces apoptosis in cancer cells. (Rac) -Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation, such as neurodegenerative diseases, cardiac disorders, viral and protozoan infections, glomerulonephritis, and chronic inflammation[1].
Product Specifications
CAS Number
186692-44-4
Product Name Alternative
(Rac) -Seliciclib; (Rac) -CYC202
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Apoptosis; CDK
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Smiles
CCC(NC1=NC(NCC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1)CO
Molecular Formula
C19H26N6O
Molecular Weight
354.45
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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