Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Senicapoc (Standard)

Senicapoc (Standard) is the analytical standard of Senicapoc. This product is intended for research and analytical applications. Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM[1].

Product Specifications

CAS Number

289656-45-7

UNSPSC

12352100

Target

Potassium Channel; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Others

Smiles

O=C(C(C1=CC=CC=C1)(C2=CC=C(C=C2)F)C3=CC=C(F)C=C3)N

Molecular Formula

C20H15F2NO

Molecular Weight

323.34

References & Citations

[1]Stocker JW, et al. ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice. Blood. 2003 Mar 15;101 (6) :2412-8.|[2]Van Der Velden J, et al. K (Ca) 3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. PLoS One. 2013 Jun 24;8 (6) :e66886.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PPM1A (NM_021003) Human Recombinant Protein
TP720139M 50 µg

PPM1A (NM_021003) Human Recombinant Protein

Sign In for Pricing
View Details
PARD3 Polyclonal Antibody
E-AB-40193-01 25 µL

PARD3 Polyclonal Antibody

Sign In for Pricing
View Details
PARD3 Polyclonal Antibody
E-AB-40193-02 100 µL

PARD3 Polyclonal Antibody

Sign In for Pricing
View Details
OR11A1 Human Gene Knockout Kit (CRISPR)
KN423230 1 Kit

OR11A1 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Orbital Shaker BSOT-607
BSOT-607 1 Unit

Orbital Shaker BSOT-607

Sign In for Pricing
View Details
CD14 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3F5]
TA811518AM 100 µL

CD14 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3F5]

Sign In for Pricing
View Details