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CAY10734

CAY10734 is the agonist for sphingosine-1-phosphate receptor 1 (S1P1) with an IC50 of 1.3 nM. CAY10734 promotes the recirculation of peripheral blood lymphocytes, and is a potential immunosuppressant[1].

Product Specifications

CAS Number

635701-59-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

LPL Receptor

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Smiles

O=C(O)C1CN(C1)CC2=CC=C(C=C2)C3=NOC(C4=CC=C(CC(C)C)C=C4)=N3

Molecular Formula

C23H25N3O3

Molecular Weight

391.46

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Li Z, et al., Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3. J Med Chem. 2005 Oct 6;48 (20) :6169-73.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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