HOKU-81 (Standard)
HOKU-81 (Standard) is the analytical standard of HOKU-81. This product is intended for research and analytical applications. HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol. HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect[1][2].
Product Specifications
CAS Number
58020-43-2
UNSPSC
12352100
Target
Adrenergic Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease; Endocrinology
Smiles
ClC1=C(C(O)CNC(C)(C)C)C=CC(O)=C1
Molecular Formula
C12H18ClNO2
Molecular Weight
243.73
References & Citations
[1]Kubo S, Matsubara I, Yamazaki M et al. Pharmacological studies of 1- (2-chloro-4-hydroxyphenyl) -2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions. Arzneimittelforschung. 1980;30 (8) :1272-8.|[2]Gomi Y, Shirahase H, Funato H. Effects of 1- (2-chloro-4-hydroxyphenyl) -t-butylaminoethanol (HOKU-81), a new bronchodilator, on isolated trachea and atria of guinea pig. Jpn J Pharmacol. 1979 Aug;29 (4) :515-24.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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