HOKU-81 (Standard)

HOKU-81 (Standard) is the analytical standard of HOKU-81. This product is intended for research and analytical applications. HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810) . HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect[1][2].

Product Specifications

CAS Number

[58020-43-2]

UNSPSC

12352100

Target

Adrenergic Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cardiovascular Disease; Endocrinology

Smiles

ClC1=C(C(O)CNC(C)(C)C)C=CC(O)=C1

Molecular Formula

C12H18ClNO2

Molecular Weight

243.73

References & Citations

[1]Kubo S, Matsubara I, Yamazaki M et al. Pharmacological studies of 1- (2-chloro-4-hydroxyphenyl) -2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions. Arzneimittelforschung. 1980;30 (8) :1272-8.|[2]Gomi Y, Shirahase H, Funato H. Effects of 1- (2-chloro-4-hydroxyphenyl) -t-butylaminoethanol (HOKU-81), a new bronchodilator, on isolated trachea and atria of guinea pig. Jpn J Pharmacol. 1979 Aug;29 (4) :515-24.