Sorbinil (Standard)
Sorbinil (Standard) is the analytical standard of Sorbinil. This product is intended for research and analytical applications. Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway[1][2].
Product Specifications
CAS Number
[68367-52-2]
UNSPSC
12352100
Target
Aldose Reductase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C([C@@]12C3=CC(F)=CC=C3OCC1)NC(N2)=O
Molecular Formula
C11H9FN2O3
Molecular Weight
236.20
References & Citations
[1]Huang Q, et al. Sorbinil, an Aldose Reductase Inhibitor, in Fighting Against Diabetic Complications. Med Chem. 2019;15 (1) :3-7.|[2]Chang KC, et al. Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues. Chem Biol Interact. 2013 Feb 25;202 (1-3) :283-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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