Sorbinil (Standard)

Sorbinil (Standard) is the analytical standard of Sorbinil. This product is intended for research and analytical applications. Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway[1][2].

Product Specifications

CAS Number

[68367-52-2]

UNSPSC

12352100

Target

Aldose Reductase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C([C@@]12C3=CC(F)=CC=C3OCC1)NC(N2)=O

Molecular Formula

C11H9FN2O3

Molecular Weight

236.20

References & Citations

[1]Huang Q, et al. Sorbinil, an Aldose Reductase Inhibitor, in Fighting Against Diabetic Complications. Med Chem. 2019;15 (1) :3-7.|[2]Chang KC, et al. Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues. Chem Biol Interact. 2013 Feb 25;202 (1-3) :283-7.