Hydrouracil- (4-Br-2,6-difluorobenzene)
Hydrouracil- (4-Br-2,6-difluorobenzene) is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil- (4-Br-2,6-difluorobenzene) can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[1499388-70-3]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(=O)CCN1C2=C(F)C=C(Br)C=C2F
Molecular Formula
C10H7BrF2N2O2
Molecular Weight
305.08
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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