3,9-Dimethyl-3,9-diazaspiro[5.5]undecane
3,9-Dimethyl-3,9-diazaspiro[5.5]undecane is a rigid PROTAC linker can be used in the synthesis of PROTACs, such as FIP22 (HY-175764) . FIP22 is a potent and selective IRAK4 PROTAC degrader with anti- atopic dermatitis activity[1].
Product Specifications
CAS Number
[93004-48-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Inflammation/Immunology
Purity
99.98
Smiles
CN(CC1)CCC21CCN(C)CC2
Molecular Formula
C11H22N2
Molecular Weight
182.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Fan Y, et al. Discovery of Rigid Linker-Based IRAK4 PROTACs with Improved Metabolic Stability for the Treatment of Inflammatory Diseases. J Med Chem. 2025 Aug 28;68 (16) :17874-17896.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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