TBuO-Ste-Glu (AEEA-AEEA-OH) -OtBu
TBuO-Ste-Glu (AEEA-AEEA-OH) -OtBu is an intermediate in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist Semaglutide (HY-114118) .
Product Specifications
CAS Number
[1118767-16-0]
Product Name Alternative
Semaglutide side chain
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
GLP Receptor
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
98.04
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(O)COCCOCCNC(COCCOCCNC(CC[C@@H](C(OC(C)(C)C)=O)NC(CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O)=O)=O)=O
Molecular Formula
C43H79N3O13
Molecular Weight
846.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Thomas B Kjeldsen, et al. Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320. J Med Chem. 2021 Jan 14;64 (1) :616-628.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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