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E3 ligase Ligand 63

E3 ligase Ligand 63 is an E3 ligase ligand that can be used to synthesize CDK2 degrader 2 (HY-163815) [1].

Product Specifications

CAS Number

[2304754-51-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.80

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

O=C(C(N1C2=CC=CC(Br)=C2N(C)C1=O)CC3)NC3=O

Molecular Formula

C13H12BrN3O3

Molecular Weight

338.16

Precautions

H302, H315, H319

References & Citations

[1]Philip Collier, et al., Cdk2 degraders and uses thereof. WO2024039901A2

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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