3-Fluoro-desmethyl-cabozantinib
3-Fluoro-desmethyl-cabozantinib is an BCL6 ligand that can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961) [1].
Product Specifications
CAS Number
[849217-50-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Met/HGFR; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Purity
99.63
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1(CC1)C(NC2=CC=C(C(F)=C2)OC3=C4C=C(OC)C(O)=CC4=NC=C3)=O)NC5=CC=C(C=C5)F
Molecular Formula
C27H21F2N3O5
Molecular Weight
505.47
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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