Thioaspirine
Thioaspirine is a carbonic anhydrase (CA) inhibitor with Kis of 64.3 and 10.9 μM for hCA II and hCA IX, respectively. Thioaspirine effectively relieves the inflammatory pain in CFA -treated mice. Thioaspirine can be used for inflammatory pain research[1].
Product Specifications
CAS Number
55819-78-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(O)C1=CC=CC=C1SC(C)=O
Molecular Formula
C9H8O3S
Molecular Weight
196.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lucarini E, et al. Study of Chalcogen Aspirin Derivatives with Carbonic Anhydrase Inhibitory Properties for Treating Inflammatory Pain. ACS Med Chem Lett. 2024 Aug 14;15 (9) :1559-1565. doi: 10.1021/acsmedchemlett.4c00284. Erratum in: ACS Med Chem Lett. 2025 Jan 03;16 (2) :347.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
CA II; CA IX
Frequently Asked Questions
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