Thioaspirine

Thioaspirine is a carbonic anhydrase (CA) inhibitor with Kis of 64.3 and 10.9 μM for hCA II and hCA IX, respectively. Thioaspirine effectively relieves the inflammatory pain in CFA (HY-153808) -treated mice. Thioaspirine can be used for inflammatory pain research[1].

Product Specifications

CAS Number

[55819-78-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(O)C1=CC=CC=C1SC(C)=O

Molecular Formula

C9H8O3S

Molecular Weight

196.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Lucarini E, et al. Study of Chalcogen Aspirin Derivatives with Carbonic Anhydrase Inhibitory Properties for Treating Inflammatory Pain. ACS Med Chem Lett. 2024 Aug 14;15 (9) :1559-1565. doi: 10.1021/acsmedchemlett.4c00284. Erratum in: ACS Med Chem Lett. 2025 Jan 03;16 (2) :347.